Sirukumab Rheumatoid Arthritis Market Analysis and Forecast to 2023 offers “Sirukumab (Rheumatoid Arthritis) – Forecast and Market Analysis to 2023”global research report on its store.

Rheumatoid arthritis (RA) is a chronic autoimmune disease which causes inflammation and deformity of the joints . It affects over seven million individuals in the 10MM covered in this report (US, France, Germany, Italy, Spain, UK, Japan, Australia, China, and India) and the prevalence is expected to grow to just over 8.5 million individuals by 2023. The anti-TNFs have been effective in treating the signs and symptoms of RA and inhibiting progression to erosive bone disease. However, the landscape is quickly changing with the introduction of biosimilars, novel biologics, and a class of oral therapies known as JAK inhibitors, all of which will change the market dynamics between 2013 and 2023. With the anti-TNFs as extremely effective therapies for RA, the market is extremely competitive for new entrants and will undergo further pressure as biosimilars are approved and launch.

Sirukumab is an SC, anti-IL-6 human mAb developed by Centocor, now Janssen (a subsidiary of J&J). In December 2011, GlaxoSmithKline (GSK) and J&J’s Janssen Biologics entered into a collaboration to co-develop sirukumab for RA. It is now in Phase III trials for patients with moderate to severe RA who have failed either MTX monotherapy or treatment with MTX combined with a biologic. Sirukumab differentiates itself as a biologic that targets the IL-6 cytokine, rather than targeting the IL-6 receptor, as do Sirukumab and Actemra.

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Scope of The Report:

  • Overview of Rheumatoid Arthritis, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  • Detailed information on Sirukumab including product description, safety and efficacy profiles as well as a SWOT analysis.
  • Sales forecast for Sirukumab for the top 10 countries from 2013 to 2023.
  • Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan, Australia, China and India.

Reasons to Buy This Report:

  • Understand and capitalize by identifying products that are most likely to ensure a robust return.
  • Stay ahead of the competition by understanding the changing competitive landscape for Rheumatoid Arthritis.
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential.
  • Make more informed business decisions from insightful and in-depth analysis of Sirukumab performance.
  • Obtain sales forecast for Sirukumab from 2013-2023 in top 10 countries (the US, France, Germany, Italy, Spain, the UK and Japan, Australia, China and India).

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Table of Content for “Sirukumab (Rheumatoid Arthritis) – Forecast and Market Analysis to 2023” research report includes:

3 Disease Overview 15

3.1 Etiology and Pathophysiology 15

3.1.1 Etiology 15

3.1.2 Pathophysiology 15

3.2 Symptoms 20

3.3 Prognosis 21

3.4 Quality of Life 21

4 Disease Management 22

4.1 Diagnosis and Treatment Overview 22

4.1.1 Diagnosis 22

4.1.2 Treatment Guidelines 24

4.1.3 Leading Prescribed Drugs for the Treatment of RA 34

4.1.4 Clinical Practice 35

5 Competitive Assessment 41

5.1 Overview 41

6 Unmet Need and Opportunity 43

6.1 Overview 43

6.2 Development of Cost-Effective Therapies 44

6.2.1 Unmet Need 44

6.2.2 Gap Analysis 45

6.2.3 Opportunity 45

6.3 Biomarkers to Predict Responsiveness to Therapy 45

6.3.1 Unmet Need 45

6.3.2 Gap Analysis 47

6.3.3 Opportunity 48

6.4 Early Diagnosis of RA 48

6.4.1 Unmet Need 48

6.4.2 Gap Analysis 49

6.4.3 Opportunity 50

6.5 Personalized Treatment Approach 51

6.5.1 Unmet Need 51

6.5.2 Gap Analysis 51

6.5.3 Opportunity 53

7 Pipeline Assessment 55

7.1 Overview 55

7.2 Promising Drugs in Clinical Development 55

8 Sirukumab 63

8.1 Overview 63

8.2 Efficacy 64

8.3 Safety 65

8.4 Dosing and Formulation 66

8.5 Potential Clinical Positioning 66

8.6 Potential Commercial Positioning 66

8.7 Pricing and Reimbursement 67

8.8 SWOT Analysis 68

8.9 Forecast 68

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