Xeljanz (tofacitinib) Rheumatoid Arthritis Market Analysis and Forecast to 2023 offers “Xeljanz (tofacitinib) (Rheumatoid Arthritis) – Forecast and Market Analysis to 2023”global research report on its store.

Rheumatoid arthritis (RA) is a chronic autoimmune disease which causes inflammation and deformity of the joints . It affects over seven million individuals in the 10MM covered in this report (US, France, Germany, Italy, Spain, UK, Japan, Australia, China, and India) and the prevalence is expected to grow to just over 8.5 million individuals by 2023. The anti-TNFs have been effective in treating the signs and symptoms of RA and inhibiting progression to erosive bone disease. However, the landscape is quickly changing with the introduction of biosimilars, novel biologics, and a class of oral therapies known as JAK inhibitors, all of which will change the market dynamics between 2013 and 2023. With the anti-TNFs as extremely effective therapies for RA, the market is extremely competitive for new entrants and will undergo further pressure as biosimilars are approved and launch.

Xeljanz (tofacitinib, formerly known as tasocitinib) is an oral, small-molecule inhibitor of JAK3 developed by Pfizer. Xeljanz is a first-in-class drug that was approved for the treatment of RA in the US in 2012, and in Japan in 2013. It is also in development for the treatment of psoriasis (as a topical and oral formulation), psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, atopic dermatitis, and juvenile idiopathic arthritis in the seven major markets (7MM; US, 5EU, and Japan).

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Scope of The Report:

  • Overview of Rheumatoid Arthritis, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  • Detailed information on Xeljanz (tofacitinib) including product description, safety and efficacy profiles as well as a SWOT analysis.
  • Sales forecast for Xeljanz (tofacitinib) for the top 2 countries from 2013 to 2023.
  • Sales information covered for the US and Japan.

Reasons to Buy This Report:

  • Understand and capitalize by identifying products that are most likely to ensure a robust return.
  • Stay ahead of the competition by understanding the changing competitive landscape for Rheumatoid Arthritis.
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential.
  • Make more informed business decisions from insightful and in-depth analysis of Xeljanz (tofacitinib) performance.
  • Obtain sales forecast for Xeljanz (tofacitinib) from 2013-2023 in top 2 countries (the US and Japan).

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Table of Content for “Xeljanz (tofacitinib) (Rheumatoid Arthritis) – Forecast and Market Analysis to 2023” research report includes:

3 Disease Overview 14

3.1 Etiology and Pathophysiology 14

3.1.1 Etiology 14

3.1.2 Pathophysiology 14

3.2 Symptoms 19

3.3 Prognosis 20

3.4 Quality of Life 20

4 Disease Management 21

4.1 Diagnosis and Treatment Overview 21

4.1.1 Diagnosis 21

4.1.2 Treatment Guidelines 23

4.1.3 Leading Prescribed Drugs for the Treatment of RA 33

4.1.4 Clinical Practice 34

5 Competitive Assessment 40

5.1 Overview 40

6 Xeljanz (tofacitinib) 42

6.1 Overview 42

6.2 Efficacy 45

6.3 Safety 47

6.4 SWOT Analysis 48

6.5 Forecast 48

1.1 List of Tables

Table 1: Symptoms of RA 19

Table 2: 1987 ACR Diagnostic Criteria for RA 22

Table 3: 2010 ACR/EULAR Diagnostic Criteria for RA 23

Table 4: Treatment Guidelines for RA Used by Each Country in the 10MM 26

Table 5: ACR 2012 Criteria for RA Remission and Low/Moderate/High Disease Activity 29

Table 6: EULAR 2013 Criteria for RA Remission 30

Table 7: Most Prescribed Biologics for RA (After csDMARDs) in the Global Markets, 2014 34

Table 8: Leading Branded Treatments for RA 2014 41

Table 9: Product Profile - Xeljanz 45

Table 10: ORAL Standard ACR20 Responses for Tofacitinib vs. Humira and Placebo at Month 6 46

Table 11: ORAL Step ACR20, 50, and 70 Responses for Xeljanz vs. Placebo at Month 6 46

Table 12: Xeljanz SWOT Analysis, 2014 48

Table 13: Global Sales Forecasts ($m) for Xeljanz, 2013-2023 49

Table 14: High-Prescribing Physicians (non-KOLs) Surveyed, By Country 61

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