07 June, 2014: New scientific study recommends middle-aged couples with problems to conceive to go directly into in vitro fertilization (IVF) treatment, and to avoid any other type of fertility therapy.
Scientists have discovered that females aged 38 and older were two times more likely to conceive with IVF within their first 2 cycles of therapy than if they used oral or injectable fertility medicines and the same goes for completing an effective birth from that pregnancy. "In this age group, time really is of the essence," stated lead analyst Marlene Goldman, a teacher of obstetrics and gynaecology at Dartmouth's Geisel School of Medicine, in Lebanon who also said that opting for a more reliable treatment faster is the best route for infertile couples to take, and stated that by the end of the trial, more than 4 out of 5 children that were effectively born had actually been conceived by undergoing IVF treatment.
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A test representative explained that the regular progression of fertility therapy requires artificial insemination incorporated with the oral fertility drug clomiphene first, followed by insemination accompanied by injectable medicines called gonadotropins or follicle-stimulating hormones (FSH), and that if those 2 techniques were to fail, physicians would only then proceed to IVF treatment, whereby the females egg and the males sperm are joined in a lab dish, and the resulting embryo is then implanted into the mother's womb.
The research study, which was funded by the U.S. National Institutes of Health, was released online April 29 in the publication Fertility and Sterility. In this study, 154 middle-aged couples with inexplicable infertility problems at two Boston fertility centers were arbitrarily split into 3 groups. One group received oral fertility treatment, the second injectable medication and the third went straight to IVF treatment. The participating couples needed to have actually been trying to conceive for a minimum of six months, without formerly using any of the treatments in the research study. The female partner had to be in-between 38 and 42, and both partners needed to be in fairly good reproductive health.
Within 2 cycles, 49 percent of those who underwent IVF treatment became pregnant and 31 percent delivered, 22 percent of those with oral medication conceived and 16 percent delivered, and 17 percent of those given injectable medication conceived and 14 percent delivered. All couples that had not succeeded in their very first two cycles of any therapy then went on to undergo IVF in their subsequent treatment cycles. The couples in the original IVF treatment group of the study wound up needing 36 percent fewer complete cycles before conception than the couples who started with oral or injectable medication. By the end of the therapy, 71 percent of all couples in the study had developed a scientific pregnancy and 46 percent delivered at least one live-born infant. About 84 percent of all live births in the research came about as an outcome of couples undergoing IVF treatment.
You can find more information about recent technical advances in IVF treatment on the IVF-Spain website, where you are also welcome to take a free online consultation or speak directly to a member of the English speaking staff based at the IVF-Spain clinic in Alicante.
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