The “Protein Expression Market by Expression Systems (Mammalian, Prokaryotic, Baculovirus, Yeast), by Products (Expression Vector, Service, Reagent), by Application (Industrial, Therapeutic) by End User (Pharmaceutical, Biotechnology, CRO) - Global Forecast to 2018” provides a detailed overview of the major drivers, restraints, challenges, opportunities, current market trends, and strategies impacting the global protein expression market along with the estimates and forecasts of the revenue and share analysis.
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The global protein expression market is expected to grow at a CAGR of 8.83% between 2013 and 2018, to reach $1,396.68 million by 2018.
The report segments this market by expression systems, products, applications, and end users. The expression system segment includes insect, mammalian, prokaryotic, yeast, and others. Of these, the prokaryotic segment commanded the largest share of the global market, by expression in 2013. The use of E.coli as the preferred host cell for large quantity and cheap protein expression and production has accounted for the highest share of prokaryotic expression systems. The mammalian segment is poised to grow at the highest CAGR between 2013 and 2018. With the rise in demand for therapeutic proteins, the need for proteins with appropriate post-translational modifications will increase, thus driving the speedy growth of the mammalian expression systems.
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The product segments included in this report are competent cells, expression vectors, instruments, reagents, and services. The reagents segment commanded the largest share of the global market in 2013, while the services segment is poised to grow at the highest CAGR between 2013 and 2018. Since chemical transfection is easier and less expensive, chemical reagents are used for transfections and maintenance of cell lines in large numbers. Also, the large numbers of reagents in the markets is because the consumption of reagents is a recurring event as opposed to the relatively less consumption of vectors and competent host cells. As companies have now started to offer services that provide custom optimization of protein expression, emerging research labs and companies who lack resources and expertise will be highly benefitted. Since the market is expected to grow at a CAGR of 8.83% between 2013 and 2018, the increasing need will boost the growth of the services offered by companies.
The applications segment of the protein expression market includes industrial proteins, research applications, and therapeutic proteins. Of these, therapeutic proteins segment commanded the largest share of the global market in 2013 and is also poised to grow at the highest CAGR between 2013 and 2018. Therapeutic proteins serve a highly specific and complex set of functions that cannot be mimicked by simple chemical compound. Therapeutic proteins have higher immuntolerance and are ideally suited therapeutic candidates. Owing to the versatile advantages of therapeutic proteins over small molecule drugs to alleviate diseases, the therapeutic proteins application is expected to continue growing at the highest CAGR.
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The end-user segments included in this report are academic research, contract research organizations, pharmaceutical and biotechnological companies, and others. Of these, the pharmaceutical and biotechnological companies segment commanded the largest share of the global protein expression market in 2013, while the contract research organizations segment is poised to grow at the highest CAGR between 2013 and 2018. Protein expression finds primary application in the research and development of commercial proteins for use in pharmaceuticals and biotechnology. As such, pharmaceutical and biotechnological companies hold the highest share of global market. With the increasing outsourcing by pharmaceutical and biotechnological companies and the lack of resources and expertise in the emerging pharmaceutical companies, contract research organizations which provide relatively less expensive resources and expertise are expected to grow at the highest CAGR.
Based on geography, the global protein expression market is segmented into Asia, Europe, North America, and Rest of the World (RoW). The Asia segment includes the regional segments of China, India, Japan, and Rest of Asia (RoA). The Europe segment is further divided into the regional segments of France, Germany, Italy, Spain, the U.K., and the Rest of Europe (RoE). North America is further divided into regional segments of Canada and U.S. The Rest of the World (RoW) segment is further divided into the regional segments of Latin America, Middle East and Africa, and Pacific countries.
The global market is expected to grow at a CAGR of 8.83% between 2013 and 2018, to reach $1,396.68 million in 2018. Protein expression is an integral part of proteomics that facilitates research by allowing the expression of genetically engineered recombinant proteins in a diverse range of host cells. On account of the decreasing R&D productivity and the patent cliff sales drop, increasing research intensity in the pharmaceutical sector will be an important growth driver for this market during the forecast period between 2013 and 2018. In addition, the growth in the biologics and proteomics market will enhance the research in protein expression, thus enabling it to be a major growth driver. However, the decline in R&D expenditure and the high consolidation in the market are restraining the market.
The major players in the protein expression market are Agilent Technologies, Inc. (U.S.), Bio-Rad Laboratories (U.S.), Life Technologies Corporation (U.S.), Merck Millipore (U.S.), New England Biolabs, Inc. (U.S.), Promega Corporation (U.S.), QIAGEN (Netherlands), Sigma-Aldrich Corporation (U.S.), Takara Bio, Inc. (Japan), and Thermo Fisher Scientific, Inc. (U.S.).
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